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Anaplasmosis

moderate

A bacterial infection carried by the same blacklegged tick that transmits Lyme disease. Cases often involve both at once. Looks like a bad flu without respiratory symptoms. Treatable with doxycycline; can be severe in older or immunocompromised patients.

Pathogen
Anaplasma phagocytophilum (bacterium)
Vector
Blacklegged tick (Ixodes scapularis)
Onset
1–2 weeks after the bite.

What it is

Anaplasmosis is caused by a bacterium that infects a specific kind of white blood cell. The vector is the blacklegged tick — the same species responsible for Lyme disease — so the geography of risk overlaps almost completely with Lyme. A single tick can carry both, which is why co-infections are common.

How long the tick has to be attached

Like Lyme, anaplasmosis transmission generally requires extended attachment — on the order of 24 hours. Quick removal cuts the risk dramatically.

The first signs to watch for

One to two weeks after a bite, anaplasmosis comes on like a bad flu:

  • High fever
  • Severe headache
  • Muscle aches
  • Chills and shaking
  • Fatigue
  • Sometimes nausea or vomiting

Notably absent: cough, sore throat, runny nose. If a flu-like illness in summer doesn’t have respiratory symptoms, anaplasmosis is on the differential — especially after outdoor time. Lab work typically shows low platelets, low white-cell count, and elevated liver enzymes.

When to see a doctor

This week:a flu-like illness with high fever and severe headache, one to two weeks after time outdoors in a Lyme area, with no respiratory symptoms. Tell your doctor about the exposure — anaplasmosis isn’t always front of mind.

Emergency room: confusion, severe shortness of breath, or signs of shock. Severe anaplasmosis can damage organs, especially in older or immunocompromised patients.

What your doctor will do

Anaplasmosis is treated with doxycycline. Most people respond within 24–48 hours of starting antibiotics. Diagnosis is usually clinical (symptoms plus exposure history) with confirmation from blood work — treatment shouldn’t wait for the lab result.

Where it shows up in Canada

Anaplasmosis follows the blacklegged tick: southern Ontario, southern Quebec, Nova Scotia, and New Brunswick, with emerging activity in southeastern Manitoba and the BC south coast. Quebec’s Estrie region in particular has seen a notable rise over the past several years.

Public Health Agency of Canada (anaplasmosis health-professional guidance); Canada Communicable Disease Report (Estrie regional case series).

Related

Last reviewed

General information only — not medical advice. In an emergency, call 911. Read the full disclaimer.

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